Calnexin 抗体 (N-Term)
Quick Overview for Calnexin 抗体 (N-Term) (ABIN7650431)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-300, N-Term
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原理
- Calnexin (Endoplasmic Reticulum Marker)(CANX/1543)
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产品特性
- Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER). It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Calnexin (CANX)
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别名
- Calnexin
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背景
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Synonyms: Calnexin, CANX, IP90, Major histocompatibility complex class I antigen-binding protein p88
Gene Symbol: CANX
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分子量
- 67 kDa (predicted), 80-90 kDa (observed)
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基因ID
- 821
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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