BMI1 抗体 (AA 142-326)
Quick Overview for BMI1 抗体 (AA 142-326) (ABIN7650105)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 142-326
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原理
- BMI1 (Oncogene and Stem Cell Marker)(BMI1/2689)
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产品特性
- The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human BMI1 protein (around aa 142-326)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: 293T, NIH3T3, HeLa or Jurkat cells. Colon Carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- BMI1
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背景
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Synonyms: BMI1, Polycomb complex protein BMI1, B lymphoma Mo MLV insertion region 1 homolog, BMI1 polycomb ring finger oncogene, Polycomb group ring finger 4, RING finger protein 51
Gene Symbol: BMI1
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分子量
- ~41 kDa
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基因ID
- 648
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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