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BMI1 抗体 (AA 142-326)

This 小鼠 单克隆 anti-BMI1 antibody (Clone BMI1-2823) specifically detects BMI1 in WB, IHC, IF 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7650104
发货至: 中国
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Quick Overview for BMI1 抗体 (AA 142-326) (ABIN7650104)

抗原

See all BMI1 抗体
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

适用

  • 141
  • 53
  • 37
  • 10
  • 8
  • 7
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 86
  • 53
  • 5
小鼠

克隆类型

  • 75
  • 69
单克隆

标记

  • 81
  • 10
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This BMI1 antibody is un-conjugated

应用范围

  • 112
  • 75
  • 40
  • 37
  • 28
  • 23
  • 11
  • 11
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

BMI1-2823
  • 抗原表位

    • 35
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 142-326

    原理

    BMI1 (Oncogene and Stem Cell Marker)(BMI1/2823)

    产品特性

    The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (around aa 142-326) of human BMI1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa or Jurkat cells. Colon Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    别名

    BMI1

    背景

    Synonyms: BMI1, Polycomb complex protein BMI1, B lymphoma Mo MLV insertion region 1 homolog, BMI1 polycomb ring finger oncogene, Polycomb group ring finger 4, RING finger protein 51

    Gene Symbol: BMI1

    分子量

    ~41 kDa

    基因ID

    648

    UniProt

    P35226

    途径

    Cell Division Cycle, Autophagy
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