Recombinant AMACR 抗体 (AA 297-394) (CF®568)
Quick Overview for Recombinant AMACR 抗体 (AA 297-394) (CF®568) (ABIN7649405)
抗原
See all AMACR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 297-394
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原理
- AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF568 conjugate
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产品特性
- This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and betbeta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human AMACR protein fragment (around aa 297-394)
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亚型
- IgG
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anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1864 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1723 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 1-198) antibodyAMACR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人, 小鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 2A10F3 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351) antibodyAMACR 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 312-326) antibodyVerified AMACR 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rAMACR-1864 unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Monoclonal AMACR-2748R unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351), (C-Term) antibodyAMACR 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18736 unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HEK cells or Prostate Adenocarcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- AMACR
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背景
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Synonyms: Alpha-methylacyl-CoA Racemase, AMACR, p504S, CBAS4, RACE
Gene Symbol: AMACR
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分子量
- 42 kDa
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基因ID
- 23600
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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