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DDX58 抗体 (AA 201-300)

Name: DDX58 抗体 (AA 201-300)
SKU: ABIN730663
Availability: OutOfStock

This anti-DDX58 antibody is a 兔多克隆 antibody detecting DDX58 in WB, ELISA 和 IHC (p). Suitable for 小鼠.

Immunohistochemistry (IHC) image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 201-300) antibody (ABIN730663) (DDX58 抗体 (AA 201-300))

IHC

IHC (p)

2 images

产品编号 ABIN730663

发货至: 中国

Datasheet as PDF

Quick Overview for DDX58 抗体 (AA 201-300) (ABIN730663)

抗原

See all DDX58 抗体

DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

适用

小鼠

宿主

兔

克隆类型

多克隆

标记

This DDX58 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product DDX58 Primary Antibody

抗原表位
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AA 201-300

交叉反应

小鼠

预测反应

Human,Rat,Dog,Cow,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human DDX58

亚型

IgG
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 550-776) antibody
DDX58 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 1-211) antibody
DDX58 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) antibody
DDX58 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 6C1 unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (C-Term) antibody
Verified DDX58 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 789-925) antibody
DDX58 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4G1B6 unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (C-Term) antibody
DDX58 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 726-925) antibody
DDX58 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 200-250) antibody
DDX58 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (N-Term) antibody
DDX58 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 201-713) antibody
DDX58 适用: 人, 小鼠 WB, IHC, IP 宿主: 小鼠 Monoclonal Alme-1 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

别名

DDX58

背景

Synonyms: RIGI, RIG-I, RLR-1, SGMRT2, Probable ATP-dependent RNA helicase DDX58, DEAD box protein 58, RIG-I-like receptor 1, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, DDX58
Background: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include: 5'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5'-triphosphate moiety, blunt-end base pairing at the 5'-end of the RNA is very essential. Overhangs at the non-triphosphorylated end of the dsRNA RNA have no major impact on its activity. A 3'overhang at the 5'triphosphate end decreases and any 5'overhang at the 5' triphosphate end abolishes its activity. Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs), IFN-alpha and IFN-beta. Detects both positive and negative strand RNA viruses including members of the families Paramyxoviridae: Human respiratory syncytial virus and measles virus (MeV), Rhabdoviridae: vesicular stomatitis virus (VSV), Orthomyxoviridae: influenza A and B virus, Flaviviridae: Japanese encephalitis virus (JEV), hepatitis C virus (HCV), dengue virus (DENV) and west Nile virus (WNV). It also detects rotavirus and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome such as Epstein-Barr virus (EBV). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). May play important roles in granulocyte production and differentiation, bacterial phagocytosis and in the regulation of cell migration.

基因ID

23586

UniProt

O95786

途径

Activation of Innate immune Response, Hepatitis C