AMACR 抗体
Quick Overview for AMACR 抗体 (ABIN728863)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
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预测反应
- Human,Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse AMACR
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亚型
- IgG
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应用备注
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- AMACR
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背景
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Synonyms: 2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl-CoA racemase deficiency, included, Alpha-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase isoform 1, P504S, Amacr, AMACR, AMACR deficiency, included, CBAS4, P504S, RACE, 2 arylpropionyl CoA epimerase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl CoA racemase, AMACR_HUMAN, EC 5.1.99.4, Da1-8, RACE, RM, Macr 1, Macr1, Methylacyl CoA racemase alpha.
Background: alpha-methylacyl-CoA racemase(AMACR/P504S) is Prostate-specific antigen (PSA) screening for prostate cancer is now widespread in the United States among men of all ages. However PSA has limited specificity because benign disease, including prostatic enlargement and inflammation, can increase PSA levels. Thus, a more specific prostate cancer markers is needed. One such potential marker is AMACR, an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids. Recent studies have shown that, compared with expression in normal or benign prostate epithelium, AMACR is consistently overexpressed in prostate cancer epithelium, making it a specific marker for cancer cells within the prostate gland. Furthermore, overexpression of AMACR may increase the risk of prostate cancer because its expression is increased in premalignant lesions (prostatic intraepithelial neoplasia).
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基因ID
- 23600
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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