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MUC1 抗体 (Biotin)

This anti-MUC1 antibody is a Human Chimeric antibody detecting MUC1 in FACS. Suitable for 人.
产品编号 ABIN7608319
发货至: 中国

Quick Overview for MUC1 抗体 (Biotin) (ABIN7608319)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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Human, 兔

克隆类型

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Chimeric

标记

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This MUC1 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

DMC493
  • 原理

    Biotinylated Anti-MUC1 antibody(DMC493), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1:100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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