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IL-6 Receptor 抗体 (Biotin)

This anti-IL-6 Receptor antibody is a 兔 单克隆 antibody detecting IL-6 Receptor in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7608293
发货至: 中国

Quick Overview for IL-6 Receptor 抗体 (Biotin) (ABIN7608293)

抗原

See all IL-6 Receptor (IL6R) 抗体
IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

适用

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宿主

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克隆类型

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单克隆

标记

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This IL-6 Receptor antibody is conjugated to Biotin

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

DM152
  • 原理

    Biotinylated Anti-IL6R antibody(DM152), Rabbit mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG
  • 应用备注

    ELISA 1:5000-10000, Flow Cyt 1:100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

    别名

    IL6R

    背景

    This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST:GP130:IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

    UniProt

    P08887

    途径

    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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