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RAD50 抗体

This anti-RAD50 antibody is a 兔 单克隆 antibody detecting RAD50 in WB, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7606123
发货至: 中国

Quick Overview for RAD50 抗体 (ABIN7606123)

抗原

See all RAD50 抗体
RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This RAD50 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

ACCG-18
  • 原理

    Anti-Rad50 Monoclonal Antibody

    产品特性

    Anti-Rad50 Monoclonal Antibody (ABIN7606123). Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Rad50 Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000
    ICC/IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    浓度

    Lot specific

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

    别名

    RAD50

    背景

    Synonyms: Ubiquitin-like modifier-activating enzyme ATG7,ATG12-activating enzyme E1 ATG7,Autophagy-related protein 7,APG7-like,hAGP7,Ubiquitin-activating enzyme E1-like protein,ATG7,APG7L,

    Tissue Specificity: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. .

    分子量

    35 kDa

    UniProt

    Q92878

    途径

    DNA Damage Repair, Protein targeting to Nucleus
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