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S100A8 抗体

This anti-S100A8 antibody is a 兔 单克隆 antibody detecting S100A8 in WB, IHC 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7605595
发货至: 中国

Quick Overview for S100A8 抗体 (ABIN7605595)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

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人, 小鼠

宿主

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克隆类型

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单克隆

标记

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This S100A8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

CFC-19
  • 原理

    Anti-MRP8 S100A8 Rabbit Monoclonal Antibody

    产品特性

    Anti-MRP8 A8 Rabbit Monoclonal Antibody (ABIN7605595). Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human MRP8

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000
    IHC 1:50-1:200
    IP 1:30

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    浓度

    Lot specific

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    S100A8

    背景

    Synonyms: Protein S100-A8,Calgranulin-A,Calprotectin L1L subunit,Cystic fibrosis antigen,CFAG,Leukocyte L1 complex light chain,Migration inhibitory factor-related protein 8,MRP-8,p8,S100 calcium-binding protein A8,Urinary stone protein band A,Protein S100-A8, N-terminally processed,S100A8,CAGA, CFAG, MRP8,

    Tissue Specificity: Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers. .

    分子量

    52 kDa

    UniProt

    P05109

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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