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Insulin Receptor 抗体

This anti-Insulin Receptor antibody is a 兔 单克隆 antibody detecting Insulin Receptor in WB, ICC 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN7605279
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (ABIN7605279)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 大鼠

宿主

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克隆类型

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单克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

GGA-9
  • 原理

    Anti-Insulin Receptor INSR Rabbit Monoclonal Antibody

    产品特性

    Anti-Insulin Receptor INSR Rabbit Monoclonal Antibody (ABIN7605279). Tested in WB, ICC/IF applications. This antibody reacts with Human, Rat.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Insulin Receptor

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000
    ICC/IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    浓度

    Lot specific

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR

    背景

    Synonyms: Insulin receptor,IR,2.7.10.1,CD220,Insulin receptor subunit alpha,Insulin receptor subunit beta,INSR,

    Tissue Specificity: Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas. .

    分子量

    73 kDa

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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