FADD 抗体
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北京 101111
Quick Overview for FADD 抗体 (ABIN7604813)
抗原
See all FADD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-FADD Monoclonal Antibody
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产品特性
- Anti-FADD Monoclonal Antibody. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000IHC 1:50-1:200ICC/IF 1:50-1:200IP 1:50FC 1:50
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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别名
- FADD
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背景
- Fas associated via death domain
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分子量
- 100-110 kDa
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基因ID
- 8772
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UniProt
- Q13158
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途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
抗原
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