IL23R 抗体
Quick Overview for IL23R 抗体 (ABIN7603758)
抗原
See all IL23R 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Anti-IL23 Receptor/IL23R Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-IL23 Receptor/IL23R Antibody Picoband® (ABIN7603758). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human IL23 Receptor/IL23R recombinant protein (Position: Q76-Q 305).
-
亚型
- IgG
-
-
anti-Interleukin 23 Receptor (IL23R) (AA 405-629) antibody
IL23R 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) (AA 401-550) antibodyIL23R 适用: 人, 小鼠, 犬 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) (AA 15-125) antibodyIL23R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) antibodyIL23R 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) (AA 25-355) antibodyIL23R 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) (N-Term) antibodyIL23R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) antibodyIL23R 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) antibodyIL23R 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) (N-Term) antibodyIL23R 适用: 人, 小鼠 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 23 Receptor (IL23R) (AA 553-628) antibodyIL23R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12 unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. (Dec 2006). "A genome-wide association study identifies IL23R as an inflammatory bowel disease gene". Science. 314 (5804): 1461-3. 2. Momozawa Y, Mni M, Nakamura K, Coppieters W, Almer S, Amininejad L, et al. (Jan 2011). "Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease". Nature Genetics. 43 (1): 43-7. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- IL23R (Interleukin 23 Receptor (IL23R))
-
别名
- IL23R
-
背景
-
Synonyms: Interleukin-23 receptor, IL-23 receptor, IL-23R, Il23r,
Tissue Specificity: Expressed by Th1, Th2 and dendritic cells.
Background: Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
-
分子量
- 72 kDa
-
基因ID
- 149233
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
-
