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SMC1A 抗体 (pSer957)

This anti-SMC1A antibody is a 兔 单克隆 antibody detecting SMC1A in WB, IHC, IF 和 ICC. Suitable for 人.
产品编号 ABIN7603375
发货至: 中国

Quick Overview for SMC1A 抗体 (pSer957) (ABIN7603375)

抗原

See all SMC1A 抗体
SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

适用

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宿主

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克隆类型

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单克隆

标记

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This SMC1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

FCI-19
  • 抗原表位

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    pSer957

    原理

    Anti-Phospho-SMC1 (S957) Monoclonal Antibody

    产品特性

    Anti-Phospho-SMC1 Monoclonal Antibody (ABIN7603375). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Phospho-SMC1 (S957) Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000
    IHC 1:50-1:200
    ICC/IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

    别名

    SMC1A

    背景

    Synonyms: Red fluorescent protein eqFP611,GFP-like chromoprotein,

    Tissue Specificity: Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .

    分子量

    15 kDa

    UniProt

    Q14683

    途径

    Stem Cell Maintenance
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