SMC1A 抗体 (C-Term)
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北京 101111
Quick Overview for SMC1A 抗体 (C-Term) (ABIN2780766)
抗原
See all SMC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SMC1A Antibody - C-terminal region
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序列
- VISLKEEFYT KAESLIGVYP EQGDCVISKV LTFDLTKYPD ANPNPNEQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against SMC1A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SMC1A
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anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibody
SMC1A 适用: 人, 小鼠 WB, IHC, ICC, FACS, IF (p), IP 宿主: 兔 Monoclonal BL-205-2G8 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodyKD Validated SMC1A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2670 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer966) antibodySMC1A 适用: 人 WB, IP, IHC (fp), IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (AA 1183-1233) antibodySMC1A 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 山羊 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人 WB, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8C11 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (N-Term) antibodySMC1A 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38780-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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别名
- SMC1A
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背景
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Background Information: The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by SMC1A gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the SMC1A protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Structural maintenance of chromosomes 1A
Alternative Symbols: SMC1, SMCB, CDLS2, DEE85, SB1.8, EIEE85, SMC1L1, DXS423E, SMC1alpha
Protein Name: Structural maintenance of chromosomes protein 1A
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分子量
- 143kDa
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基因ID
- 8243
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NCBI登录号
- NP_006297
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UniProt
- Q14683
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途径
- Stem Cell Maintenance
抗原
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