TLR8 抗体 (N-Term)
Quick Overview for TLR8 抗体 (N-Term) (ABIN7603239)
抗原
See all TLR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-TLR8 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TLR8 Antibody Picoband® (ABIN7603239). Tested in IHC applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at N-terminus of human TLR8, which shares 76.5% amino acid (aa) sequence identity with mouse TLR8.
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亚型
- IgG
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anti-Toll-Like Receptor 8 (TLR8) (AA 849-1041) antibody
TLR8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 723-825) antibodyTLR8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Toll-Like Receptor 8 (TLR8) (C-Term) antibodyTLR8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 844-1039) antibodyTLR8 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 844-1039) antibodyTLR8 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 750-850) antibody (PE)TLR8 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal 44C143 PE
anti-Toll-Like Receptor 8 (TLR8) (AA 957-987) antibodyTLR8 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (AA 434-463) antibodyTLR8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (Middle Region) antibodyTLR8 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 8 (TLR8) (C-Term) antibodyTLR8 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 山羊, 豚鼠, 马, 绵羊, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
1. Chuang, T.-H., Ulevitch, R. J.Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9.Europ. Cytokine Netw. 11: 372-378, 2000. 2. Kadowaki, N., Ho, S., Antonenko, S., de Waal Malefyt, R., Kastelein, R. A., Bazan, F., Liu, Y.-J.Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens.J. Exp. Med. 194: 863-869, 2001. 3. Peng, G., Guo, Z., Kiniwa, Y., Voo, K., Peng, W., Fu, T., Wang, D. Y., Li, Y., Wang, H. Y., Wang, R.-F.Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function.Science 309: 1380-1384, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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别名
- TLR8
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背景
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Synonyms: Nuclear factor 1 B-type, NF1-B, Nuclear factor 1/B, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/B, NF-I/B, NFI-B, TGGCA-binding protein, NFIB
Background: TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288).The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.
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分子量
- 60 kDa
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基因ID
- 51311
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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