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RAD23A 抗体 (N-Term)

This anti-RAD23A antibody is a 兔 多克隆 antibody detecting RAD23A in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7603222
发货至: 中国

Quick Overview for RAD23A 抗体 (N-Term) (ABIN7603222)

抗原

See all RAD23A 抗体
RAD23A (RAD23 Homolog A (RAD23A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This RAD23A antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-hHR23A/RAD23A Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-hHR23A/RAD23A Antibody Picoband® (ABIN7603222). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human hHR23A/RAD23A, identical to the related mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
    1. Bergink, S., Theil, A. F., Toussaint, W., De Cuyper, I. M., Kulu, D. I., Clapes, T., van der Linden, R., Demmers, J. A., Mul, E. P., van Alphen, F. P., Marteijn, J. A., van Gent, T., Maas, A., Robin, C., Philipsen, S., Vermeulen, W., Mitchell, J. R., Gutierrez, L. Erythropoietic defect associated with reduced cell proliferation in mice lacking the 26S proteasome shuttling factor Rad23b. Molec. Cell. Biol. 33: 3879-3892, 2013. 2. Chen, L., Madura, K. Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B. FEBS Lett. 580: 3401-3408, 2006. 3. Masutani, C., Sugasawa, K., Yanagisawa, J., Sonoyama, T., Ui, M., Enomoto, T., Takio, K., Tanaka, K., van der Spek, P. J., Bootsma, D., Hoeijmakers, J. H. J., Hanaoka, F. Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23. EMBO J. 13: 1831-1843, 1994.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    RAD23A (RAD23 Homolog A (RAD23A))

    别名

    RAD23A

    背景

    Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968

    Tissue Specificity: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.

    Background: UV excision repair protein RAD23 homolog A is a protein that in humans is encoded by the RAD23A gene. The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms.

    分子量

    60 kDa

    基因ID

    5886

    UniProt

    P54725

    途径

    DNA Damage Repair
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