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CD44 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects CD44 in FACS, WB, IF 和 ICC. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7603137
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD44 抗体 (N-Term) (ABIN7603137)

抗原

See all CD44 抗体
CD44

适用

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人, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

7H7
  • 抗原表位

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    N-Term

    原理

    Anti-CD44 Antibody (monoclonal, 7H7)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CD44 Antibody (monoclonal, 7H7) (ABIN7603137). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human CD44, different from the related mouse and rat sequences by two amino acids.

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD44

    别名

    CD44

    背景

    Synonyms: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1

    Tissue Specificity: Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level).

    Background: CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

    分子量

    82 kDa

    基因ID

    960

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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