MAPK14 抗体 (C-Term)
Quick Overview for MAPK14 抗体 (C-Term) (ABIN7602908)
抗原
See all MAPK14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-p38 alpha/MAPK14 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-p38 alpha/MAPK14 Antibody Picoband® (ABIN7602908). Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human p38 alpha/MAPK14, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (pThr180), (pTyr182) antibody
MAPK14 适用: 人, 小鼠, 大鼠, 小鸡, 山羊 WB, ELISA, IHC (p), FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibodyMAPK14 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8G4D11 unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 141-240) antibodyMAPK14 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 19-279) antibodyMAPK14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 260-360) antibodyMAPK14 适用: 人 WB, ELISA, IP, IHC (p), PLA 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibodyMAPK14 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 10B11C8 unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 1-360) antibodyMAPK14 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (C-Term) antibodyMAPK14 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 295-324), (C-Term) antibodyMAPK14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB2723 unconjugated
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibodyMAPK14 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Adams, R. H., Porras, A., Alonso, G., Jones, M., Vintersten, K., Panelli, S., Valladares, A., Perez, L., Klein, R., Nebreda, A. R. Essential role of p38-alpha MAP kinase in placental but not embryonic cardiovascular development. Molec. Cell 6: 109-116, 2000. 2. Agrawal, A., Lingappa, J., Leppla, S. H., Agrawal, S., Jabbar, A., Quinn, C., Pulendran, B. Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin. Nature 424: 329-334, 2003. 3. Anhalt, G. J., Labib, R. S., Voorhees, J. J., Beals, T. F., Diaz, L. A. Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease. New Eng. J. Med. 306: 1189-1196, 1982. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
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别名
- MAPK14
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背景
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Synonyms: Mannose-6-phosphate isomerase,5.3.1.8,Phosphohexomutase,Phosphomannose isomerase,PMI,MPI,PMI1,
Tissue Specificity: Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
Background: Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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分子量
- 38 kDa
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基因ID
- 1432
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UniProt
- Q16539
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
抗原
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