IDH2 抗体 (C-Term)
Quick Overview for IDH2 抗体 (C-Term) (ABIN7602787)
抗原
See all IDH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Anti-IDH2 Antibody Picoband® (monoclonal, 6B13)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IDH2 Antibody Picoband® (monoclonal, 6B13) (ABIN7602787). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human IDH2, identical to the related mouse and rat sequences.
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亚型
- IgG2a
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anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 40-452) antibody
IDH2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 193-452) antibodyIDH2 适用: 人 WB, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 1-143) antibodyIDH2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3E8E9 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-451) antibodyIDH2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 413-447), (C-Term) antibodyIDH2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-452) antibodyIDH2 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (Middle Region) antibodyIDH2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 251-350) antibodyIDH2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 193-452) antibodyIDH2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (Internal Region) antibodyVerified IDH2 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial". 2. Xu X, Zhao J, Xu Z, Peng B, Huang Q, Arnold E, Ding J (Aug 2004). "Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity". The Journal of Biological Chemistry 279 (32): 33946-57. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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别名
- IDH2
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背景
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Synonyms: T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.
Background: Isocitrate dehydrogenase [NADP], mitochondrialis anenzymethat in humans is encoded by theIDH2gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
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分子量
- 45 kDa
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基因ID
- 3418
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UniProt
- P48735
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途径
- Warburg Effect
抗原
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