MASP2 抗体 (C-Term)
Quick Overview for MASP2 抗体 (C-Term) (ABIN7602762)
抗原
See all MASP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-MASP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MASP2 Antibody Picoband® (ABIN7602762). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MASP2, which shares 88% and 76% amino acid (aa) sequence identity with mouse and rat MASP2, respectively.
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亚型
- IgG
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anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 351-450) antibody
MASP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 280-433) antibodyMASP2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 445-683) antibodyMASP2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 170-287) antibodyMASP2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 189-314) antibodyMASP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 1-686) antibodyMASP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (Internal Region) antibodyMASP2 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (N-Term) antibodyMASP2 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 280-433) antibodyMASP2 适用: 人 WB 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 201-250) antibodyMASP2 适用: 人, 小鼠, Cow, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Stover, C. M., Schwaeble, W. J., Lynch, N. J., Thiel, S., Speicher, M. R. Assignment of the gene encoding mannan-binding lectin-associated serine protease 2 (MASP2) to human chromosome 1p36.3-p36.2 by in situ hybridization and somatic cell hybrid analysis. Cytogenet. Cell Genet. 84: 148-149, 1999. 2. Stover, C. M., Thiel, S., Thelen, M., Lynch, N. J., Vorup-Jensen, T., Jensenius, J. C., Schwaeble, W. J. Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene. J. Immun. 162: 3481-3490, 1999. 3. Takahashi, M., Endo, Y., Fujita, T., Matsushita, M. A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway. Int. Immun. 11: 859-863, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
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别名
- MASP2
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背景
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Synonyms: Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2, MASP2
Tissue Specificity: Plasma.
Background: Mannan-binding lectin serine protease 2 is a protein that in humans is encoded by the MASP2 gene. This gene is mapped to 1p36.22. This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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分子量
- 76 kDa
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基因ID
- 10747
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UniProt
- O00187
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途径
- Complement System
抗原
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