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NLRX1 抗体 (AA 98-874)

This anti-NLRX1 antibody is a 兔 多克隆 antibody detecting NLRX1 in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7602716
发货至: 中国

Quick Overview for NLRX1 抗体 (AA 98-874) (ABIN7602716)

抗原

See all NLRX1 抗体
NLRX1 (NLR Family Member X1 (NLRX1))

适用

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人, 大鼠, 小鼠

宿主

  • 45
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克隆类型

  • 46
多克隆

标记

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This NLRX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 5
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    AA 98-874

    原理

    Anti-NLRX1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-NLRX1 Antibody Picoband® (ABIN7602716). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NLRX1 recombinant protein (Position: R98-E874).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Guo, H., Konig, R., Deng, M., Riess, M., Mo, J., Zhang, L., Petrucelli, A., Yoh, S. M., Barefoot, B., Samo, M., Sempowski, G. D., Zhang, A., and 14 others. NLRX1 sequesters STING to negatively regulate the interferon response, thereby facilitating the replication of HIV-1 and DNA viruses. Cell Host Microbe 19: 515-528, 2016. 2. Inohara, N., Chamaillard, M., McDonald, C., Nunez, G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Ann. Rev. Biochem. 74: 355-383, 2005. 3. Leber, A., Hontecillas, R., Tubau-Juni, N., Zoccoli-Rodriguez, V., Hulver, M., McMillan, R., Eden, K., Allen, I. C., Bassaganya-Riera, J. NLRX1 regulates effector and metabolic functions of CD4+ T cells. J. Immun. 198: 2260-2268, 2017.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    NLRX1 (NLR Family Member X1 (NLRX1))

    别名

    NLRX1

    背景

    Synonyms: Transmembrane protein 107,TMEM107,DC20, UNQ638/PRO1268,

    Tissue Specificity: Ubiquitous. .

    Background: NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene. The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene.

    分子量

    108 kDa

    基因ID

    79671

    途径

    SARS-CoV-2 Protein Interactome
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