NLRX1 抗体 (Internal Region)
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- 抗原 See all NLRX1 抗体
- NLRX1 (NLR Family Member X1 (NLRX1))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- NLRX1 Antibody detects endogenous levels of total NLRX1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NLRX1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NLRX1 Primary Antibody
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anti-NLR Family Member X1 (NLRX1) (AA 581-630) antibody
NLRX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 580-630) antibodyNLRX1 适用: 人, 大鼠, 小鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 111-210) antibodyNLRX1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 45-205) antibodyNLRX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (Internal Region) antibodyVerified NLRX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NLRX1 (NLR Family Member X1 (NLRX1))
- 别名
- NLRX1 (NLRX1 产品)
- 别名
- CLR11.3 antibody, DLNB26 antibody, NOD26 antibody, NOD5 antibody, NOD9 antibody, BC034204 antibody, RGD1311293 antibody, NLR family member X1 antibody, NLRX1 antibody, nlrx1 antibody, Nlrx1 antibody
- 背景
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Description: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12 (PubMed:22749352). Regulates also MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis (PubMed:27393910). Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
Gene: NLRX1
- 分子量
- 100-110 kDa
- 基因ID
- 79671
- UniProt
- Q86UT6
- 途径
- SARS-CoV-2 Protein Interactome
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