IRF5 抗体 (AA 98-477)
Quick Overview for IRF5 抗体 (AA 98-477) (ABIN7602715)
抗原
See all IRF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 98-477
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原理
- Anti-IRF5 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-IRF5 Antibody Picoband® (ABIN7602715). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IRF5 recombinant protein (Position: R98-A477). Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.
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亚型
- IgG
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anti-Interferon Regulatory Factor 5 (IRF5) (AA 395-504) antibody
IRF5 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 395-504) antibodyIRF5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (C-Term) antibodyVerified IRF5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 81-108) antibodyIRF5 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 214-395) antibodyIRF5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) antibodyIRF5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 176-240) antibodyIRF5 适用: 人 WB, ELISA, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 10T1 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 1-498) antibodyIRF5 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 1-200) antibodyIRF5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) antibodyIRF5 适用: 人 WB, IHC (p) 宿主: 兔 Monoclonal 3F11 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Couzinet, A., Tamura, K., Chen, H., Nishimura, K., Wang, Z., Morishita, Y., Takeda, K., Yagita, H., Yanai, H., Taniguchi, T., Tamura, T. A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis. Proc. Nat. Acad. Sci. 105: 2556-2561, 2008. 2. Sigurdsson, S., Goring, H. H. H., Kristjansdottir, G., Milani, L., Nordmark, G., Sandling, J. K., Eloranta, M.-L., Feng, D., Sangster-Guity, N., Gunnarsson, I., Svenungsson, E., Sturfelt, G., Jonsen, A., Truedsson, L., Barnes, B. J., Alm, G., Ronnblom, L., Syvanen, A.-C. Comprehensive evaluation of the genetic variants of interferon regulatory growth factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus. Hum. Molec. Genet. 17: 872-881, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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别名
- IRF5
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.
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分子量
- 60 kDa
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基因ID
- 3663
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UniProt
- Q13568
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途径
- TLR signaling, Autophagy
抗原
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