TXNRD1 抗体 (AA 93-326)
Quick Overview for TXNRD1 抗体 (AA 93-326) (ABIN7602673)
抗原
See all TXNRD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 93-326
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原理
- Anti-TXNRD1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-TXNRD1 Antibody Picoband® (ABIN7602673). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TXNRD1 recombinant protein (Position: Y93-Y326).
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亚型
- IgG
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anti-Thioredoxin Reductase 1 (TXNRD1) (AA 374-577) antibody
TXNRD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 451-550) antibodyTXNRD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) antibodyTXNRD1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 208-433) antibodyTXNRD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) antibodyTXNRD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) antibodyTXNRD1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (C-Term) antibodyVerified TXNRD1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 161-647) antibodyTXNRD1 适用: 人 WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal AT30F1 unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) antibodyTXNRD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 271-305) antibodyTXNRD1 适用: 人 WB 宿主: 兔 Polyclonal RB56182 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dammeyer, P., Damdimopoulos, A. E., Nordman, T., Jimenez, A., Miranda-Vizuete, A., Arner, E. S. J. Induction of cell membrane protrusions by the N-terminal glutaredoxin domain of a rare splice variant of human thioredoxin reductase 1. J. Biol. Chem. 283: 2814-2821, 2008. 2. Gasdaska, J. R., Gasdaska, P. Y., Gallegos, A., Powis, G. Human thioredoxin reductase gene localization to chromosomal position 12q23-q24.1 and mRNA distribution in human tissue. Genomics 37: 257-259, 1996. 3. Gasdaska, P. Y., Gasdaska, J. R., Cochran, S., Powis, G. Cloning and sequencing of a human thioredoxin reductase. FEBS Lett. 373: 5-9, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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别名
- TXNRD1
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背景
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Synonyms: TXNRD1, GRIM12, KDRF, Thioredoxin reductase 1, cytoplasmic, TR, EC 1.8.1.9, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin reductase TR1
Background: Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms, including a glutaredoxin-containing isoform that is predominantly expressed in testis.
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分子量
- 65 kDa
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基因ID
- 7296
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UniProt
- Q16881
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途径
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
抗原
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