MAP2K5 抗体 (AA 9-442)
Quick Overview for MAP2K5 抗体 (AA 9-442) (ABIN7602630)
抗原
See all MAP2K5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-442
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原理
- Anti-MEK5/MAP2K5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MEK5/MAP2K5 Antibody Picoband® (ABIN7602630). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MEK5/MAP2K5 recombinant protein (Position: F9-R442).
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 251-350) antibody
MAP2K5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-448) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-E6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 385-412), (C-Term) antibodyMAP2K5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (pSer137) antibodyMAP2K5 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 311-315) antibodyMAP2K5 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Zhou, G., Bao, Z. Q., Dixon, J. E. Components of a new human protein kinase signal transduction pathway. J. Biol. Chem. 270: 12665-12669, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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别名
- MAP2K5
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背景
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Synonyms: Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2
Tissue Specificity: Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium.
Background: Dual specificity mitogen-activated protein kinase kinase 5 is an enzyme that in humans is encoded by the MAP2K5 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
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分子量
- 50 kDa
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基因ID
- 5607
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UniProt
- Q13163
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway
抗原
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