KPNB1 抗体 (AA 8-876)
Quick Overview for KPNB1 抗体 (AA 8-876) (ABIN7602501)
抗原
See all KPNB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 8-876
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原理
- Anti-KPNB1 Antibody Picoband® (monoclonal, 3I11F2)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-KPNB1 Antibody Picoband® (monoclonal, 3I11F2) (ABIN7602501). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KPNB1 recombinant protein (Position: E8-A876).
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亚型
- IgG2b
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anti-Karyopherin (Importin) beta 1 (KPNB1) (C-Term) antibody
Verified KPNB1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 250-350) antibodyKPNB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 9-214) antibodyKPNB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) antibodyKPNB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) antibodyKPNB1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 190-216), (N-Term) antibodyKPNB1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20681 unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) antibodyKPNB1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 190-216) antibodyKPNB1 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 144-193) antibodyKPNB1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 21-441) antibodyKPNB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Ayala-Madrigal, M. L., Doerr, S., Ramirez-Duenas, M. L., Hansmann, I. Assignment of KPNA4 and KPNB1 encoding karyopherin alpha 4 and beta 1 to human chromosome bands 11q22 and 17q21 respectively, by in situ hybridization. Cytogenet. Cell Genet. 89: 258-259, 2000. 2. Bayliss, R., Littlewood, T., Stewart, M. Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell 102: 99-108, 2000. 3. Caudron, M., Bunt, G., Bastiaens, P., Karsenti, E. Spatial coordination of spindle assembly by chromosome-mediated signaling gradients. Science 309: 1373-1376, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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别名
- KPNB1
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背景
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Synonyms: Peroxiredoxin-6,1.11.1.15,1-Cys peroxiredoxin,1-Cys PRX,24 kDa protein,Acidic calcium-independent phospholipase A2,aiPLA2,3.1.1.-,Antioxidant protein 2,Liver 2D page spot 40,Non-selenium glutathione peroxidase,NSGPx,1.11.1.9,Red blood cells page spot 12,PRDX6,AOP2, KIAA0106,
Tissue Specificity: Widely expressed in fetal and adult tissues.
Background: Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 97 kDa
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基因ID
- 3837
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UniProt
- Q14974
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途径
- Protein targeting to Nucleus
抗原
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