Pleiotrophin 抗体 (AA 61-148)
Quick Overview for Pleiotrophin 抗体 (AA 61-148) (ABIN7602164)
抗原
See all Pleiotrophin (PTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-148
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原理
- Anti-PTN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PTN Antibody Picoband® (ABIN7602164). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PTN recombinant protein (Position: D61-K148).
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亚型
- IgG
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anti-Pleiotrophin (PTN) (AA 45-154) antibody
PTN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Pleiotrophin (PTN) (AA 33-168) antibodyPTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 101-168) antibodyPTN 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 33-168) antibodyPTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 33-168) antibodyPTN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 150-168), (C-Term) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 127-154), (C-Term) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB14477 unconjugated
anti-Pleiotrophin (PTN) (C-Term) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (Internal Region) antibodyVerified PTN 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: PTN pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)". 2. Vanderwinden JM, Mailleux P, Schiffmann SN, Vanderhaeghen JJ (1992). "Cellular distribution of the new growth factor pleiotrophin (HB-GAM) mRNA in developing and adult rat tissues". Anat. Embryol. 186 (4): 387-406. 3. Said EA, Courty J, Svab J, Delbé J, Krust B, Hovanessian AG (September 2005). "Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin". FEBS J. 272 (18): 4646-59. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Pleiotrophin (PTN)
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别名
- PTN
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背景
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Synonyms: Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule, HB-GAM, Heparin-binding neurite outgrowth-promoting factor 1, HBNF-1, Osteoblast-specific factor 1, OSF-1, PTN, HBNF1, NEGF1
Tissue Specificity: Osteoblast and brain.
Background: Pleiotrophin (PTN), also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM), is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.
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分子量
- 19 kDa
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基因ID
- 5764
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UniProt
- P21246
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途径
- RTK signaling
抗原
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