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Pleiotrophin 抗体 (C-Term)

PTN 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044398
发货至: 中国
  • 抗原 See all Pleiotrophin (PTN) 抗体
    Pleiotrophin (PTN)
    抗原表位
    • 14
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-168, C-Term
    适用
    • 52
    • 29
    • 28
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 大鼠
    宿主
    • 69
    • 6
    • 2
    • 2
    克隆类型
    • 72
    • 7
    多克隆
    标记
    • 36
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Pleiotrophin antibody is un-conjugated
    应用范围
    • 46
    • 26
    • 26
    • 26
    • 21
    • 16
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Pleiotrophin(PTN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    QAESKKKKKE GKKQEKMLD
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Pleiotrophin(PTN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: pleiotrophin
    Protein Name: Pleiotrophin(PTN)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Pleiotrophin(150-168aa QAESKKKKKEGKKQEKMLD), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product PTN Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." in: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

  • 抗原
    Pleiotrophin (PTN)
    别名
    PTN (PTN 产品)
    别名
    zHBNF antibody, zgc:111787 antibody, harp antibody, hbnf antibody, X-PTF antibody, hbgf8 antibody, negf1 antibody, ptn antibody, PTN antibody, HARP antibody, HBGF8 antibody, HBNF antibody, NEGF1 antibody, PTN-A antibody, HB-GAM antibody, HBBM antibody, HBGF-8 antibody, OSF-1 antibody, HBBN antibody, OSF antibody, Osf-1 antibody, Osf1 antibody, Hbnf antibody, pleiotrophin antibody, pleiotrophin L homeolog antibody, ptn antibody, PTN antibody, ptn.L antibody, Ptn antibody
    背景
    Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.

    Synonyms: HARP antibody|HB-GAM antibody|HBBM antibody|HBGAM antibody|HBGF-8 antibody|HBGF8 antibody|HBNF antibody|HBNF-1 antibody|HBNF1 antibody|Heparin binding growth associated molecule antibody|Heparin binding growth factor 8 antibody|Heparin binding neurite outgrowth promoting factor 1 antibody|Heparin-binding brain mitogen antibody|Heparin-binding growth factor 8 antibody|Heparin-binding growth-associated molecule antibody|Heparin-binding neurite outgrowth-promoting factor 1 antibody|NEGF1 antibody|Neurite growth promoting factor 1 antibody|OSF-1 antibody|OSF1 antibody|Osteoblast-specific factor 1 antibody|Pleiotrophin antibody|PTN antibody|PTN_HUMAN antibody
    UniProt
    P21246
    途径
    RTK signaling
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