NCOR2 抗体 (AA 6-2148)
Quick Overview for NCOR2 抗体 (AA 6-2148) (ABIN7602122)
抗原
See all NCOR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-2148
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原理
- Anti-NCOR2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NCOR2 Antibody Picoband® (ABIN7602122). Tested in ELISA, IF, ICC,WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NCOR2 recombinant protein (Position: Q6-H2148).
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亚型
- IgG
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anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 670-900) antibody
NCOR2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 2201-2525) antibodyNCOR2 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 1-110) antibodyNCOR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 511-560) antibodyNCOR2 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (N-Term) antibodyNCOR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (C-Term) antibodyNCOR2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 541-590) antibodyNCOR2 适用: 人, 小鼠, 大鼠, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (N-Term) antibodyNCOR2 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (AA 511-560) antibodyNCOR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, J. D., Evans, R. M. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377: 454-457, 1995. 2. Fischle, W., Dequiedt, F., Hendzel, M. J., Guenther, M. G., Lazar, M. A., Voelter, W., Verdin, E. Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. Molec. Cell 9: 45-57, 2002. 3. Hoberg, J. E., Yeung, F., Mayo, M. W. SMRT derepression by the I-kappa-B kinase alpha: a prerequisite to NF-kappa-B transcription and survival. Molec. Cell 16: 245-255, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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别名
- NCOR2
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背景
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Synonyms: Caspase recruitment domain-containing protein 9. Hcard9. CARD9
Tissue Specificity: Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Background: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 275 kDa
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基因ID
- 9612
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UniProt
- Q9Y618
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途径
- Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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