PIK3 gamma 抗体 (AA 52-308)
Quick Overview for PIK3 gamma 抗体 (AA 52-308) (ABIN7601952)
抗原
See all PIK3 gamma (PIK3CG) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 52-308
-
原理
- Anti-PI3K-gamma/PIK3CG Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-PI3K-gamma/PIK3CG Antibody Picoband® (ABIN7601952). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PI3K-gamma/PIK3CG recombinant protein (Position: K52-D308).
-
亚型
- IgG
-
-
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) antibody
PIK3CG 适用: 人, 小鼠, 猴 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) antibodyPIK3CG 适用: 人 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 4D3 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) antibodyPIK3CG 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B1 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 1-200) antibodyPIK3CG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 1-100) antibodyPIK3CG 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 1-310) antibodyPIK3CG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (C-Term) antibodyPIK3CG 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 1-100) antibodyPIK3CG 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B5D2 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (C-Term) antibodyPIK3CG 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 438-588), (Catalytic Subunit gamma) antibodyPIK3CG 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anzelon, A. N., Wu, H., Rickert, R. C. Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nature Immun. 4: 287-294, 2003. 2. Barber, D. F., Bartolome, A., Hernandez, C., Flores, J. M., Redondo, C., Fernandez-Arias, C., Camps, M., Ruckle, T., Schwarz, M. K., Rodriguez, S., Martinez-A, C., Balomenos, D., Rommel, C., Carrera, A. C. PI3K-gamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus. Nature Med. 11: 933-935, 2005. 3. Barbier, M., Attoub, S., Calvez, R., Laffargue, M., Jarry, A., Mareel, M., Altruda, F., Gespach, C., Wu, D., Lu, B., Hirsch, E., Wymann, M. P. Weakening link to colorectal cancer? Nature 413: 796 only, 2001. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
-
别名
- PIK3CG
-
背景
-
Synonyms: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94
Tissue Specificity: Selectively expressed by both resting and activated NK cells.
Background: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene. Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
-
分子量
- 126 kDa
-
基因ID
- 5294
-
UniProt
- P48736
-
途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
抗原
-
