SCYL1 抗体 (AA 5-259)
Quick Overview for SCYL1 抗体 (AA 5-259) (ABIN7601875)
抗原
See all SCYL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-259
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原理
- Anti-SCYL1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SCYL1 Antibody Picoband® (ABIN7601875). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SCYL1 recombinant protein (Position: A5-Q259).
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亚型
- IgG
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anti-SCY1-Like 1 (SCYL1) (AA 373-472) antibody
SCYL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-SCY1-Like 1 (SCYL1) antibodySCYL1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 1 (SCYL1) (AA 460-740) antibodySCYL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 1 (SCYL1) (AA 460-740) antibodySCYL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 1 (SCYL1) (AA 739-788) antibodySCYL1 适用: 人, 大鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 1 (SCYL1) (C-Term) antibodySCYL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 1 (SCYL1) (AA 156-185), (N-Term) antibodySCYL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB9791 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Di, Y., Li, J., Fang, J., Xu, Z., He, X., Zhang, F., Ling, J., Li, X., Xu, D., Li, L., Li, Y.-Y., Huo, K. Cloning and characterization of a novel gene which encodes a protein interacting with the mitosis-associated kinase-like protein NTKL. J. Hum. Genet. 48: 315-321, 2003. 2. Kato, M., Yano, K., Morotomi-Yano, K., Saito, H., Miki, Y. Identification and characterization of the human protein kinase-like gene NTKL: mitosis-specific centrosomal localization of an alternatively spliced isoform. Genomics 79: 760-767, 2002. 3. Lenz, D., McClean, P., Kansu, A., Bonnen, P. E., Ranucci, G., Thiel, C., Straub, B. K., Harting, I., Alhaddad, B., Dimitrov, B., Kotzaeridou, U., Wenning, D., and 11 others. SCYL1 variants cause a syndrome with low gamma-glutamyl-transferase cholestasis, acute liver failure, and neurodegeneration (CALFAN). Genet. Med. 20: 1255-1265, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SCYL1 (SCY1-Like 1 (SCYL1))
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别名
- SCYL1
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背景
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Synonyms: C-C chemokine receptor type 10, C-C CKR-10, CC-CKR-10, CCR-10, G-protein coupled receptor 2, CCR10, GPR2
Tissue Specificity: Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
Background: SCY1-like 1 (S. cerevisiae), also known as SCYL1, is a human gene which is highly conserved throughout evolution. This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 115 kDa
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基因ID
- 57410
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途径
- p53 Pathway
抗原
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