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ROR2 抗体 (AA 499-547)

This anti-ROR2 antibody is a 兔 多克隆 antibody detecting ROR2 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601866
发货至: 中国

Quick Overview for ROR2 抗体 (AA 499-547) (ABIN7601866)

抗原

See all ROR2 抗体
ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

适用

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人, 小鼠, 大鼠

宿主

  • 57
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克隆类型

  • 53
  • 35
多克隆

标记

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This ROR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 499-547

    原理

    Anti-ROR2 Antibody Picoband®

    产品特性

    Anti-ROR2 Antibody Picoband® (ABIN7601866). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ROR2 recombinant protein (Position: E499-Q547). Human ROR2 shares 93.9% amino acid (aa) sequence identity with mouse ROR2.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Afzal, A. R., Jeffery, S. One gene, two phenotypes: ROR2 mutations in autosomal recessive Robinow syndrome and autosomal dominant brachydactyly type B. Hum. Mutat. 22: 1-11, 2003. 2. Afzal, A. R., Rajab, A., Fenske, C. D., Oldridge, M., Elanko, N., Ternes-Pereira, E., Tuysuz, B., Murday, V. A., Patton, M. A., Wilkie, A. O. M., Jeffery, S. Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2. Nature Genet. 25: 419-422, 2000. 3. Ali, B. R., Jeffery, S., Patel, N., Tinworth, L. E., Meguid, N., Patton, M. A., Afzal, A. R. Novel Robinow syndrome causing mutations in the proximal region of the frizzled-like domain of ROR2 are retained in the endoplasmic reticulum. Hum. Genet. 122: 389-395, 2007.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

    别名

    ROR2

    背景

    Tyrosine-protein kinase transmembrane receptor ROR2, also known as neurotrophic tyrosine kinase, receptor-related 2, is a protein that in humans is encoded by the ROR2 gene located on position 9 of the long arm of chromosome 9. The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

    分子量

    105 kDa

    基因ID

    4920

    UniProt

    Q01974

    途径

    RTK signaling, WNT signaling
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