SSH1 抗体 (AA 489-921)
Quick Overview for SSH1 抗体 (AA 489-921) (ABIN7601846)
抗原
See all SSH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 489-921
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原理
- Anti-SSH1 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-SSH1 Antibody Picoband® (ABIN7600347). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SSH1 recombinant protein (Position: E489-Y921). Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.
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亚型
- IgG
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anti-Slingshot Homolog 1 (SSH1) (AA 752-849) antibody
SSH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 950-1049) antibodySSH1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 1032-1044) antibodySSH1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6C11G9 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 1032-1044) antibodySSH1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1A5C8 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 928-1049) antibodySSH1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 227-254), (N-Term) antibodySSH1 适用: 人 WB 宿主: 兔 Polyclonal RB40522 unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 1-1049) antibodySSH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Slingshot Homolog 1 (SSH1) (AA 1-1049) antibodySSH1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Niwa, R., Nagata-Ohashi, K., Takeichi, M., Mizuno, K., Uemura, T. Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell 108: 233-246, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SSH1 (Slingshot Homolog 1 (SSH1))
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别名
- SSH1
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Protein phosphatase Slingshot homolog 1 is an enzyme that in humans is encoded by the SSH1 gene. The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 150 kDa
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基因ID
- 54434
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途径
- CXCR4-mediated Signaling Events
抗原
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