IGF2R 抗体 (AA 424-529)
Quick Overview for IGF2R 抗体 (AA 424-529) (ABIN7601705)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 424-529
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原理
- Anti-IGF2R Antibody Picoband® (monoclonal, 4I11)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IGF2R Antibody Picoband® (monoclonal, 4I11) (ABIN7601705). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human IGF2R recombinant protein (Position: F424-R529).
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亚型
- IgG2a
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anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody
IGF2R 适用: 人, Non-Human Primate WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-238 unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 424-529) antibodyIGF2R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2327-2491) antibodyIGF2R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibodyIGF2R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 160-311) antibodyIGF2R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F1G1 unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2441-2490) antibodyIGF2R 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (FITC)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 FITC
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (PE)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 PE
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (APC)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 APC
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2475-2491), (C-Term) antibodyIGF2R 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Killian, J. K., Oka, Y., Jang, H.-S., Fu, X., Waterland, R. A., Sohda, T., Sakaguchi, S., Jirtle, R. L. Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations. Hum. Mutat. 18: 25-31, 2001. 2. Latos, P. A., Pauler, F. M., Koerner, M. V., Senergin, H. B., Hudson, Q. J., Stocsits, R. R., Allhoff, W., Stricker, S. H., Klement, R. M., Warczok, K. E., Aumayr, K., Pasierbek, P., Barlow, D. P. Airn transcriptional overlap, but not its IncRNA products, induces imprinted Igf2r silencing. Science 338: 1469-1472, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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别名
- IGF2R
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背景
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Synonyms: Heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1B
Tissue Specificity: Ubiquitous.
Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
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分子量
- 274 kDa
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基因ID
- 3482
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UniProt
- P11717
抗原
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