Dual Specificity Phosphatase 3 (DUSP3) (AA 4-185) 抗体
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Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (AA 4-185) 抗体 (ABIN7601613)
抗原
See all Dual Specificity Phosphatase 3 (DUSP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-185
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原理
- Anti-DUSP3 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DUSP3.Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DUSP3 recombinant protein (Position: S4-P185).
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亚型
- IgG
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anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibody
DUSP3 适用: 人 WB 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) antibodyDUSP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-30), (N-Term) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06032 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibodyDUSP3 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (N-Term) antibodyDUSP3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 76-185) antibodyDUSP3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 14-96) antibodyDUSP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Dual Specificity Phosphatase 3 (DUSP3)
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别名
- DUSP3
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背景
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Background: Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene. It is mapped to 17q21.31. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
Gene Full Name: dual specificity phosphatase 3
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分子量
- 20 kDa
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基因ID
- 1845
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UniProt
- P51452
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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