SLAMF1 抗体 (AA 34-213)
Quick Overview for SLAMF1 抗体 (AA 34-213) (ABIN7601376)
抗原
See all SLAMF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 34-213
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原理
- Anti-SLAM/CD150/SLAMF1 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SLAM//SLAMF1 Antibody Picoband® (ABIN7601376). Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SLAM/CD150/SLAMF1 recombinant protein (Position: K34-N213).
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亚型
- IgG
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chan, B., Lanyi, A., Song, H. K., Griesbach, J., Simarro-Grande, M., Poy, F., Howie, D., Sumegi, J., Terhorst, C., Eck, M. J. SAP couples Fyn to SLAM immune receptors. Nature Cell Biol. 5: 155-160, 2003. 2. Cocks, B. G., Chang, C.-C. J., Carballido, J. M., Yssel, H., de Vries, J. E., Aversa, G. A novel receptor involved in T-cell activation. Nature 376: 260-263, 1995. 3. Ferrante, P., Fusi, M. L., Saresella, M., Caputo, D., Biasin, M., Trabattoni, D., Salvaggio, A., Clerici, E., de Vries, J. E., Aversa, G., Cazzullo, C. L., Clerici, M. Cytokine production and surface marker expression in acute and stable multiple sclerosis: altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis. J. Immun. 160: 1514-1521, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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别名
- SLAMF1
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背景
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Synonyms: Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2
Tissue Specificity: Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium.
Background: Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
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分子量
- 50 kDa
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基因ID
- 6504
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UniProt
- Q13291
抗原
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