MSK2 抗体 (AA 302-772)
Quick Overview for MSK2 抗体 (AA 302-772) (ABIN7601238)
抗原
See all MSK2 (RPS6KA4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 302-772
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原理
- Anti-MSK2/RSK-B/RPS6KA4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MSK2/RSK-B/RPS6KA4 Antibody Picoband® (ABIN7601238). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MSK2/RSK-B/RPS6KA4 recombinant protein (Position: Q302-S772).
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亚型
- IgG
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anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (AA 237-393) antibody
RPS6KA4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (pThr568) antibodyRPS6KA4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (AA 1-220) antibodyRPS6KA4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (AA 322-354) antibodyRPS6KA4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (Thr568) antibodyRPS6KA4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (pThr568) antibodyRPS6KA4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (Internal Region) antibodyRPS6KA4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (C-Term) antibodyRPS6KA4 适用: 人, Cow, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) antibodyRPS6KA4 适用: 人 DB 宿主: 小鼠 Monoclonal 2934C1a unconjugated
anti-Ribosomal Protein S6 Kinase A4 (RPS6KA4) (AA 531-580), (pThr568) antibodyRPS6KA4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Deak, M., Clifton, A. D., Lucocq, J. M., Alessi, D. R. Mitogen- and stress-activated protein kinase-1 (MSK1) is ly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17: 4426-4441, 1998. 2. Gross, M. B. Personal Communication. Baltimore, Md. 5/14/2014. 3. Pierrat, B., Correia, J. S., Mary, J.-L., Tomas-Zuber, M., Lesslauer, W. RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38-alpha mitogen-activated protein kinase (p38-alpha-MAPK). J. Biol. Chem. 273: 29661-29671, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
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别名
- RPS6KA4
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背景
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Synonyms: Spermine oxidase, Polyamine oxidase 1, PAO-1, PAOh1, Smox, Smo
Tissue Specificity: Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.
Background: Ribosomal protein S6 kinase alpha-4 is an enzyme that in humans is encoded by the RPS6KA4 gene. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 86 kDa
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基因ID
- 8986
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UniProt
- O75676
抗原
-
