ASS1 抗体 (AA 3-365)
Quick Overview for ASS1 抗体 (AA 3-365) (ABIN7601191)
抗原
See all ASS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3-365
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原理
- Anti-ASS1 Antibody Picoband® (monoclonal, 5I5)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ASS1 Antibody Picoband® (monoclonal, 5I5) (ABIN7601191). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ASS1 recombinant protein (Position: S3-S365).
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亚型
- IgG2a
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anti-Argininosuccinate Synthase 1 (ASS1) (AA 1-412) antibody
ASS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) (Internal Region) antibodyVerified ASS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) antibodyASS1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) antibodyASS1 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) (AA 192-221) antibodyASS1 适用: 人, 小鼠, 大鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB20920 unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) antibodyASS1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) (AA 192-221) antibodyASS1 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) (AA 281-310) antibodyASS1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) antibodyASS1 适用: 人, 小鼠, 大鼠, 猴 WB, FACS, IF, EIA 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Argininosuccinate Synthase 1 (ASS1) (AA 1-412) antibodyASS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Engel, K., Hohne, W., Haberle, J. Mutations and polymorphisms in the human argininosuccinate synthetase (ASS1) gene. Hum. Mutat. 30: 300-307, 2009. 2. Rabinovich, S., Adler, L., Yizhak, K., Sarver, A., Silberman, A., Agron, S., Stettner, N., Sun, Q., Brandis, A., Helbling, D., Korman, S., Itzkovitz, S., Dimmock, D., Ulitsky, I., Nagamani, S. C. S., Ruppin, E., Erez, A. Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature 527: 379-383, 2015. 3. Sase, M., Kobayashi, K., Imamura, Y., Saheki, T., Nakano, K., Miura, S., Mori, M. Level of translatable messenger RNA coding for argininosuccinate synthetase in the liver of the patients with quantitative-type citrullinemia. Hum. Genet. 69: 130-134, 1985. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ASS1 (Argininosuccinate Synthase 1 (ASS1))
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别名
- ASS1
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背景
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Synonyms: Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK
Tissue Specificity: Widely expressed. Highest level in placenta, liver, muscle and kidney.
Background: Argininosuccinate synthetase is an enzyme that in humans is encoded by the ASS1 gene. It is mapped to 9q34.11. The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
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分子量
- 47 kDa
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基因ID
- 445
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UniProt
- P00966
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途径
- Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin
抗原
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