TGFB1 抗体 (AA 279-347)
Quick Overview for TGFB1 抗体 (AA 279-347) (ABIN7601058)
抗原
See all TGFB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 279-347
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原理
- Anti-TGFB1 Antibody Picoband®
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产品特性
- Anti-TGFB1 Antibody Picoband® (ABIN7601058). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TGF Beta 1/TGFB1 recombinant protein (Position: A279-H347). Human TGF Beta 1/TGFB1 shares 100 amino acid (aa) sequence identity with both mouse and rat TGF Beta 1/TGFB1.
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anti-Transforming Growth Factor, beta 1 (TGFB1) (C-Term) antibody
TGFB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibodyTGFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 62-195) antibodyTGFB1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7F6 unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 351-390) antibodyTGFB1 适用: 人, 小鼠, 大鼠, 绵羊, 兔 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibodyTGFB1 适用: 小鼠, 大鼠, Cow, Pig, 绵羊, 豚鼠, 犬, 马, 山羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 62-195) antibodyTGFB1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibodyTGFB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (N-Term) antibodyTGFB1 适用: 人 WB, ELISA, FM 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (C-Term) antibodyTGFB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibodyTGFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D11 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Awad, M. R., El-Gamel, A., Hasleton, P., Turner, D. M., Sinnott, P. J., Hutchinson, I. V. Genotypic variation in the transforming growth factor-beta-1 gene: association with transforming growth factor-beta-1 production, fibrotic lung disease, and graft fibrosis after lung transplantation. Transplantation 66: 1014-1020, 1998. 2. Azar, S. T., Salti, I., Zantout, M. S., Major, S. Alterations in plasma transforming growth factor beta in normoalbuminuric type 1 and type 2 diabetic patients. J. Clin. Endocr. Metab. 85: 4680-4682, 2000. 3. Bernasconi, P., Torchiana, E., Confalonieri, P., Brugnoni, R., Barresi, R., Mora, M., Conelio, F., Morandi, L., Mantegazza, R. Expression of transforming growth factor-beta-1 in dystrophic patient muscles correlates with fibrosis: pathogenetic role of a fibrogenic cytokine. J. Clin. Invest. 96: 1137-1144, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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别名
- TGFB1
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背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
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分子量
- 44 kDa
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基因ID
- 7040
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UniProt
- P01137
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途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
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