TTC8 抗体 (AA 271-533)
Quick Overview for TTC8 抗体 (AA 271-533) (ABIN7601040)
抗原
See all TTC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-533
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原理
- Anti-BBS8/TTC8 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BBS8/TTC8 Antibody Picoband® (ABIN7601040). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BBS8/TTC8 recombinant protein (Position: E271-Q533).
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亚型
- IgG
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anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 416-514) antibody
TTC8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E2 unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 1-505) antibodyTTC8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 251-330) antibodyTTC8 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (Internal Region) antibodyVerified TTC8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 1-505) antibodyTTC8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 71-120) antibodyTTC8 适用: 人, 马, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ansley, S. J., Badano, J. L., Blacque, O. E., Hill, J., Hoskins, B. E., Leitch, C. C., Kim, J. C., Ross, A. J., Eichers, E. R., Teslovich, T. M., Mah, A. K., Johnsen, R. C., Cavender, J. C., Lewis, R. A., Leroux, M. R., Beales, P. L., Katsanis, N. Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature 425: 628-633, 2003. 2. Goyal, S., Jager, M., Robinson, P. N., Vanita, V. Confirmation of TTC8 as a disease gene for nonsyndromic autosomal recessive retinitis pigmentosa (RP51). Clin. Genet. 89: 454-460, 2016. 3. Jin, H., White, S. R., Shida, T., Schulz, S., Aguiar, M., Gygi, S. P., Bazan, J. F., Nachury, M. V. The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell 141: 1208-1219, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
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别名
- TTC8
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背景
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Synonyms: Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, Ppase, PPA1, IOPPP, PP
Tissue Specificity: Expressed ubiquitously.
Background: Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 is a protein that in humans is encoded by the TTC8 gene.This gene encodes a protein that has been ly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants.
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分子量
- 23 kDa
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基因ID
- 123016
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途径
- Hedgehog Signaling
抗原
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