ULBP1 抗体 (AA 27-209)
Quick Overview for ULBP1 抗体 (AA 27-209) (ABIN7600996)
抗原
See all ULBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-209
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原理
- Anti-ULBP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ULBP1 Antibody Picoband® (ABIN7600996). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ULBP1 recombinant protein (Position: W27-K209).
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亚型
- IgG
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anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibody
ULBP1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A6F11 unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibodyULBP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 26-216) antibodyULBP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 1-244) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (AA 1-234) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 1 (ULBP1) (N-Term) antibodyULBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cosman, D., Mullberg, J., Sutherland, C. L., Chin, W., Armitage, R., Fanslow, W., Kubin, M., Chalupny, N. J. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14: 123-133, 2001. 2. Deng, W., Gowen, B. G., Zhang, L., Wang, L., Lau, S., Iannello, A., Xu, J., Rovis, T. L., Xiong, N., Raulet, D. H. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection. Science 348: 136-139, 2015. 3. Lopez-Soto, A., Quinones-Lombrana, A., Lopez-Arbesu, R., Lopez-Larrea, C., Gonzalez, S. Transcriptional regulation of ULBP1, a human ligand of the NKG2D receptor. J. Biol. Chem. 281: 30419-30430, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ULBP1 (UL16 Binding Protein 1 (ULBP1))
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别名
- ULBP1
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背景
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Synonyms: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R
Tissue Specificity: Brain.
Background: UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 28 kDa
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基因ID
- 80329
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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