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ULBP1 抗体 (AA 26-216) (FITC)

ULBP1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7174680
发货至: 中国
  • 抗原 See all ULBP1 抗体
    ULBP1 (UL16 Binding Protein 1 (ULBP1))
    抗原表位
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 26-216
    适用
    • 19
    • 1
    宿主
    • 17
    • 2
    克隆类型
    • 17
    • 2
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULBP1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human UL16-binding protein 1 protein (26-216AA)
    亚型
    IgG
    Top Product
    Discover our top product ULBP1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ULBP1 (UL16 Binding Protein 1 (ULBP1))
    别名
    ULBP1 (ULBP1 产品)
    别名
    RAET1I antibody, A430108B07Rik antibody, MULT1 antibody, ULBP1 antibody, UL16 binding protein 1 antibody, UL16 binding protein 21 antibody, NKG2D ligand 1 antibody, ULBP1 antibody, ULBP21 antibody, Ulbp1 antibody, LOC100683099 antibody
    背景

    Background: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

    Aliases: Alcan beta antibody, ALCAN-beta antibody, N2DL-1 antibody, N2DL1 antibody, N2DL1_HUMAN antibody, NKG2D ligand 1 antibody, NKG2D ligand 1 precursor antibody, NKG2DL1 antibody, RAET1I antibody, Retinoic acid early transcript 1I antibody, UL16 antibody, UL16 binding protein 1 antibody, UL16-binding protein 1 antibody, ULBP1 antibody

    UniProt
    Q9BZM6
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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