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Growth Hormone Receptor 抗体 (AA 25-650)

This anti-Growth Hormone Receptor antibody is a 兔 多克隆 antibody detecting Growth Hormone Receptor in WB, ELISA 和 FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7600919
发货至: 中国

Quick Overview for Growth Hormone Receptor 抗体 (AA 25-650) (ABIN7600919)

抗原

See all Growth Hormone Receptor (GHR) 抗体
Growth Hormone Receptor (GHR)

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Growth Hormone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 25-650

    原理

    Anti-Growth hormone receptor/GHR Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Growth hormone receptor/GHR Antibody (ABIN7600919). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Growth hormone receptor/GHR recombinant protein (Position: T25-Q650).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Growth Hormone Receptor (GHR)

    别名

    Ghr

    背景

    Synonyms: Growth hormone receptor, GH receptor, Somatotropin receptor, Growth hormone-binding protein, GH-binding protein, GHBP, Serum-binding protein, Ghr

    Tissue Specificity: Expressed in lung and placenta.

    Background: Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to 15 A1, 15 1.84 cM. This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

    分子量

    130 kDa

    基因ID

    14600

    UniProt

    P16882

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
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