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CD27 抗体 (AA 24-187)

This anti-CD27 antibody is a 兔 多克隆 antibody detecting CD27 in FACS, ELISA 和 IHC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7600813
发货至: 中国

Quick Overview for CD27 抗体 (AA 24-187) (ABIN7600813)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD27 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 24-187

    原理

    Anti-Cd27 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Cd27 Antibody Picoband® (ABIN7600813). Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Cd27 recombinant protein (Position: P24-F187).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: CD27 CD27 Molecule". 2. Prasad KV, Ao Z, Yoon Y, Wu MX, Rizk M, Jacquot S, Schlossman SF (Jun 1997). "CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein". Proceedings of the National Academy of Sciences of the United States of America 94 (12): 6346-51. 3. Yamamoto H, Kishimoto T, Minamoto S (Nov 1998). "NF-kappaB activation in CD27 signaling: involvement of TNF receptor-associated factors in its signaling and identification of functional region of CD27". Journal of Immunology 161 (9): 4753-9.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    Cd27

    背景

    Synonyms: Angiopoietin-related protein 4,Angiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,HFARP,ANGPTL4,ARP4, HFARP, PGAR,PP1158, PSEC0166, UNQ171/PRO197,

    Tissue Specificity: Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney. .

    Background: CD27 is a member of the tumor necrosis factor receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. And this receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

    分子量

    45 kDa

    基因ID

    21940

    UniProt

    P41272

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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