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PKC theta 抗体 (AA 23-706)

This 兔 多克隆 anti-PKC theta antibody specifically detects PKC theta in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7600767
发货至: 中国
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Quick Overview for PKC theta 抗体 (AA 23-706) (ABIN7600767)

抗原

See all PKC theta (PRKCQ) 抗体
PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC theta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 23-706

    原理

    Anti-PKC theta/PRKCQ Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PKC theta/PRKCQ Antibody (ABIN7600767). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PKC theta/PRKCQ recombinant protein (Position: E23-S706).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

    别名

    PRKCQ

    背景

    Synonyms: Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR

    Tissue Specificity: Widely expressed, with highest levels in fetal and adult brain. Expression levels of isoform 2 and isoform 3 are much lower than those of isoform 1.

    Background: Protein kinase C theta (PKC-θ) is an enzyme that in humans is encoded by the PRKCQ gene. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

    分子量

    78 kDa

    基因ID

    5588

    UniProt

    Q04759

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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