MZB1 抗体 (AA 23-189)
Quick Overview for MZB1 抗体 (AA 23-189) (ABIN7600735)
抗原
See all MZB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-189
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原理
- Anti-MZB1 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-MZB1 Antibody Picoband® (ABIN7600735). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MZB1 recombinant protein (Position: D23-L189).
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亚型
- IgG
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anti-Marginal Zone B and B1 Cell-Specific Protein (MZB1) (AA 1-189) antibody
MZB1 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Marginal Zone B and B1 Cell-Specific Protein (MZB1) antibodyMZB1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Marginal Zone B and B1 Cell-Specific Protein (MZB1) (AA 1-50) antibodyMZB1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Marginal Zone B and B1 Cell-Specific Protein (MZB1) antibodyMZB1 适用: 人 WB, IF, ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry, 1-2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bonfoco, E., Li, E., Kolbinger, F., Cooper, N. R. Characterization of a novel proapoptotic caspase-2- and caspase-9-binding protein. J. Biol. Chem. 276: 29242-29250, 2001. 2. Flach, H., Rosenbaum, M., Duchniewicz, M., Kim, S., Zhang, S. L., Cahalan, M. D., Mittler, G., Grosschedl, R. Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. Immunity 33: 723-735, 2010. 3. Katoh, M., Katoh, M. MGC29506 gene, frequently down-regulated in intestinal-type gastric cancer, encodes secreted-type protein with conserved cysteine residues. Int. J. Oncol. 23: 235-241, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))
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别名
- MZB1
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Marginal zone B and B1 cell-specific protein is a protein that in humans is encoded by the MZB1 gene. MZB1, also named as ,PACAP, MGC29506 and pERp1, belongs to the PERP1 family. It is associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. MGC29506(PACAP) may exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. (PubMed: 11350957) MZB1 has 5 isoforms with MW 21kd and 7-13kd.
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分子量
- 19 kDa
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基因ID
- 51237
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途径
- Production of Molecular Mediator of Immune Response
抗原
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