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NCF1 抗体 (AA 22-384)

This anti-NCF1 antibody is a 兔 多克隆 antibody detecting NCF1 in WB, ELISA, IHC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600691
发货至: 中国

Quick Overview for NCF1 抗体 (AA 22-384) (ABIN7600691)

抗原

See all NCF1 抗体
NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This NCF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 22-384

    原理

    Anti-p47 phox/NCF1 Antibody Picoband®

    产品特性

    Anti-p47 phox/NCF1 Antibody Picoband® (ABIN7600691). Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human p47 phox/NCF1 recombinant protein (Position: Q22-R384). Human NCF1 shares 81% amino acid (aa) sequence identity with both mouse and rat NCF1.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Del Campo, M., Antonell, A., Magano, L. F., Munoz, F. J., Flores, R., Bayes, M., Perez Jurado, L. A. Hemizygosity at the NCF1 gene in patients with Williams-Beuren syndrome decreases their risk of hypertension. Am. J. Hum. Genet. 78: 533-542, 2006. 2. Hultqvist, M., Olofsson, P., Holmberg, J., Backstrom, B. T., Tordsson, J., Holmdahl, R. Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proc. Nat. Acad. Sci. 101: 12646-12651, 2004.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

    别名

    NCF1

    背景

    Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene. The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

    分子量

    40-50 kDa

    基因ID

    653361

    UniProt

    P14598

    途径

    PI3K-Akt Signaling
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