NCF1 抗体 (pSer359)
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Quick Overview for NCF1 抗体 (pSer359) (ABIN1531723)
抗原
See all NCF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-380, pSer359
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原理
- p47-phox (phospho Ser359) Antibody
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特异性
- Phospho-p47-phox (S359) Polyclonal Antibody detects endogenous levels of p47-phox protein only when phosphorylated at S359.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human p47 phox around the phosphorylation site of Ser359. AA range:331-380
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Multi-Functional MPT Protein as a Therapeutic Agent against Mycobacterium tuberculosis." in: Biomedicines, Vol. 9, Issue 5, (2021) (PubMed).
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- NCF1 (Neutrophil Cytosol Factor 1 (NCF1))
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别名
- p47 Phox
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背景
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Synonyms: NCF1, NOXO2, SH3PXD1A, Neutrophil cytosol factor 1, NCF-1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3
Background: The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008],
Gene Name: NCF1
Protein Name: Neutrophil cytosol factor 1
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分子量
- 44 kDa
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基因ID
- 653361
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OMIM
- 233700
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UniProt
- P14598
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途径
- PI3K-Akt Signaling
抗原
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