TIM3 抗体 (AA 22-301)
Quick Overview for TIM3 抗体 (AA 22-301) (ABIN7600687)
抗原
See all TIM3 (TIM 3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-301
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原理
- Anti-TIM 3/HAVCR2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TIM 3/HAVCR2 Antibody Picoband® (ABIN7600687). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TIM 3/HAVCR2 recombinant protein (Position: S22-P301).
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亚型
- IgG
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anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (Internal Region) antibody
Verified TIM 3 适用: 人 FACS, WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal TIM3-3113 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 167-194) antibodyTIM 3 适用: 人 WB 宿主: 兔 Polyclonal RB41963 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 7C8A7 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 224-301) antibodyTIM 3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2A7A6 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibodyTIM 3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibodyTIM 3 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-366R unconjugated Recombinant Antibody
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 FACS, WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: HAVCR2 hepatitis A virus cellular receptor 2". 2. Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK (Feb 2002). "Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease". Nature. 415 (6871): 536-41. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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别名
- HAVCR2
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背景
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Synonyms: Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3
Tissue Specificity: Expressed in T-helper type 1 (Th1) lymphocytes. Expressed on regulatory T (Treg) cells after TCR stimulation. Expressed in dendritic cells and natural killer (NK) cells. Expressed in epithelial tissues. Expression is increased on CD4+ and CD8+ T-cells in chronic hepatitis C virus (HCV) infection. In progressive HIV-1 infection, expression is up- regulated on HIV-1-specific CD8 T-cells.
Background: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
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分子量
- 55 kDa
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基因ID
- 84868
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途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
抗原
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